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Published in Renal Cell Carcinoma

Expert Opinion / Cases · March 11, 2020

Progression After Immunotherapy in Patient With Recurrent RCC

Nazli Dizman MD

 

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Nazli Dizman MD

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  • Jozef Marenčák

    Mar 13, 2020

    I have questions - why was not a complete nephrectomy but only a partial nephrectomy at the first relapse? Was the tumor removed completely or were there positive edges?
In the current state, I would consider radiotherapy
Jozef Marenčák, Assoc. Prof., MD., PhD.

  • Peggy Zuckerman

    Mar 13, 2020

    I would also wonder why post the initial and second nephrectomies that were no additional scans or, if done, why they were not reported.  In addition, there is no report as to the size of either tumors. Certainly the return of disease after two years is a clear signal of systemic disease.  At this point, it would seem a complete bone scan and CTs are necessary, so as to understand the complete situation.  Radiation seems a reasonable approach, once the extent of disease is better determined.

  • İsmail Beypınar

    Mar 14, 2020

    What is the clinical prognostic of the patient? I think the further treatment may be planned according to the risk stratification. In first place radiation therapy is appropriate for this case afterward anti-VEGF treatment may be an option if the patient have low clinical risk.

  • puthuveettil jayaprakash

    Mar 23, 2020

    Local RT to the LN and systemic therapy with a fist line TKI

  • Dec 18, 2024

    Pending Moderator approval.
    Delete

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