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Renal Cell Carcinoma
Center of Excellence
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The patient was presented at our institution's tumor board and the consensus was to proceed with palliative chemotherapy with gemcitabine/ carboplatin. It was felt that there is no role for radiation therapy at this time.
CT staging scans revealed clear chest except for granulomatous disease, multiple enlarged retroperitoneal aortocaval and paracaval lymph nodes as well as multiple bilobar metastatic lesions.
She initiated palliative chemotherapy with gemcitabine and carboplatin and tolerated well with no significant cytopenias or other untoward side effects.
E2ZWJ7LRGM80475 E2ZWJ7LRGM80475
Nov 09, 2014
Why no sunitinib.?
Brad Somer
Nov 24, 2014
Collecting duct carcinomas have a much more aggressive behavior than clear cell carcinoma. They are typically more biologically similar to transitional cell carcinoma of the renal pelvis. There are case reports of VEGF-TKIs but most experience is with chemotherapy and in a review on collecting duct tumors in Current Oncology, 20 (3), 2013, Dason et al there was 26% response rate with Gem+platinum agent.
dalila amokrane
Dec 31, 2014
we use gemcitabine +platinum agent but no response was observed in 5 patients
Nov 16, 2024
Pending Moderator approval.
Are you sure you want to delete this comment? This can't be undone.
Manjari Pandey MD
Nov 04, 2014
E2ZWJ7LRGM80475 E2ZWJ7LRGM80475
Nov 09, 2014
Brad Somer
Nov 24, 2014
dalila amokrane
Dec 31, 2014
Nov 16, 2024
Pending Moderator approval.