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Luca Licata
Feb 23, 2018
Why did she receive capecitabine and not palbociclib with fulvestrant? I would consider this combination
Martin Guerrero
Feb 27, 2018
Well that is not a proven combination. The combination with fulvestrant is with abemaciclib. In my opinion i believe she would have been a candidate to bilateral lymphadenectomy and fulvestrant only or in case she rejected surgery fulvestrant only
Juan Bares
Mar 02, 2018
Paloma 3 (The Lancet Oncology2016) is Palbociclib with Fulvestrant.
Luca Licata
Mar 02, 2018
In US and Europe palbocicllib is approved in combination with an aromatase inhibitor as initial endocrine based therapy and with fulvestrant for progressive disease following endocrine therapy.
https://www.fda.gov/Drugs/InformationOnDrugs/ApprovedDrugs/ucm549978.htm
http://www.ema.europa.eu/ema/index.jsp?curl=pages/news_and_events/news/2016/09/news_detail_002604.jsp&mid=WC0b01ac058004d5c1
If the patient received fulvestrant alone, she would be deprived of the possibility to do palbociclib thereafter...
Jan 08, 2025
Pending Moderator approval.
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Luca Licata
Feb 23, 2018
Martin Guerrero
Feb 27, 2018
Juan Bares
Mar 02, 2018
Luca Licata
Mar 02, 2018
Jan 08, 2025
Pending Moderator approval.