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Expert Opinion / Conference Coverage · June 17, 2015

ASCO 2015 Recap: Renal Cell Carcinoma

 Tony Nimeh MD
Interview by
 Eric Jonasch MD
Interview with

 

Additional Info

  1. Motzer R, Hutson T, Glen H, et al Randomized phase II, three-arm trial of lenvatinib [LEN], everolimus [EVE], and LEN+EVE in patients with metastatic renal cell carcinoma. Paper presented at: American Society of Clinical Oncology (ASCO) Annual Meeting; May 29-June 2, 2015; Chicago, IL. Abstract 4506.
  2. Bjarnason GA, Knox JJ, Kollmannsberger CK, et al. Phase II study of individualized sunitinib as first-line therapy for metastatic renal cell cancer. Paper presented at: American Society of Clinical Oncology (ASCO) Annual Meeting; May 29-June 2, 2015; Chicago, IL. Abstract 4555.
  3. Armstrong AJ, Broderick S, Eisen T, et al. Final clinical results of a randomized phase II international trial of everolimus vs. sunitinib in patients with metastatic non-clear cell renal cell carcinoma [ASPEN]. Paper presented at: American Society of Clinical Oncology (ASCO) Annual Meeting; May 29-June 2, 2015; Chicago, IL. Abstract 4507.
  4. Hammers HJ, Plimack ER, Infante JR, et al. Expanded cohort results from CheckMate 016: A phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma. Paper presented at: American Society of Clinical Oncology (ASCO) Annual Meeting; May 29-June 2, 2015; Chicago, IL. Abstract 4516.
  5. Plimack ER, Hammers HJ, Rini BI, et al. Updated survival results from a randomized, dose-ranging phase II study of nivolumab in metastatic renal cell carcinoma. Paper presented at: American Society of Clinical Oncology (ASCO) Annual Meeting; May 29-June 2, 2015; Chicago, IL. Abstract 4553.
  6. Liu X, Hoang A, Zhou L, et al. Resistance to anti-angiogenic therapy is associated with an immunosuppressive tumor microenvironment in metastatic renal cell carcinoma [published online May 26, 2015]. Cancer Immunol Res. doi: 10.1158/2326-6066.CIR-14-0244.

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