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Joseph Sassani MD
Joseph W. Sassani MD Associate Editor
Weiye Li MD, PhD
Weiye Li MD, PhD Advisory Board
Leonard Press OD, FAAO, FCOVD
Leonard J. Press OD, FAAO, FCOVD Associate Editor
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Published in Eye Care

Expert Opinion / Commentary · December 10, 2024

2024 Top Story in Eye Care: Faricimab and Gene Therapy in Retinal Diseases

Weiye Li MD, PhD

 

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Additional Info

  1. Khanani AM, Kotecha A, Chang A, et al. TENAYA and LUCERNE: Two-Year Results from the Phase 3 Neovascular Age-Related Macular Degeneration Trials of Faricimab with Treat-and-Extend Dosing in Year 2. Ophthalmology. 2024;131(8):914-926.
  2. Wong TY, Haskova Z, Asik K, et al. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials. Ophthalmology. 2024;131(6):708–723.
  3. Desideri LF, Traverso CE, Nicolò M, et al. Faricimab for the Treatment of Diabetic Macular Edema and Neovascular Age-Related Macular Degeneration. Pharmaceutics. 2023;15(5):1413.
  4. Javaheri M, Khan H, Aziz AA, et al. Real-World Efficacy and Safety of Faricimab in nAMD: Two-Year Results of the TRUCKEE Study. Paper presented at: American Academy of Ophthalmology (AAO) 2024 Annual Meeting; October 18–21, 2024; Chicago, IL. Abstract PO585.
  5. Durrani AF, Momenaei B, Wakabayashi T, et al. Conversion to Faricimab After Prior Antivascular Endothelial Growth Factor Therapy for Persistent Diabetic Macular Oedema. Br J Ophthalmol. 2024;108(9):1257–1262.
  6. Dibas A, Batabyal S, Kim S, et al. Efficacy of Intravitreal Multi-Characteristic Opsin (MCO-010) Optogenetic Gene Therapy in a Mouse Model of Leber Congenital Amaurosis. J Ocul Pharmacol Ther. 2024 Oct 23. doi: 10.1089/jop.2024.0084. Online ahead of print.
  7. PracticeUpdate Editorial Team. AAO 2024: Gene Therapy Improves Vision in Retinitis Pigmentosa (HealthDay News). PracticeUpdate Eye Care. 2024 Oct 28. Accessed November 12, 2024.

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