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Published in Primary Care

Expert Opinion / My Approach · May 31, 2022

MY APPROACH to Time Restricted Eating and Intermittent Fasting in Practice: When and How

Robert Bonakdar MD, FAAFP, FACN

 

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Additional Info

  1. Liu D, Huang Y, Huang C, et al. Calorie Restriction with or without Time-Restricted Eating in Weight Loss. N Engl J Med. 2022;386(16):1495-1504.
  2. Wei M, Brandhorst S, Shelehchi M, et al. Fasting-Mimicking Diet and Markers/Risk Factors for Aging, Diabetes, Cancer, and Cardiovascular Disease. Sci Transl Med. 2017;9(377):eaai8700.
  3. Marinac CR, Nelson SH, Breen CI, et al. Prolonged Nightly Fasting and Breast Cancer Prognosis. JAMA Oncol. 2016;2(8):1049-1055.
  4. Cienfuegos S, Gabel K, Kalam F, et al. Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trial in Adults with Obesity. Cell Metab. 2020;32(3):366-378.e3.
  5. Harvie M, Howell A. Potential Benefits and Harms of Intermittent Energy Restriction and Intermittent Fasting Amongst Obese, Overweight and Normal Weight Subjects—A Narrative Review of Human and Animal Evidence. Behav Sci (Basel). 2017;7(1):4.
  6. Sutton EF, Beyl R, Early KS, et al. Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes. Cell Metab. 2018;27(6):1212-1221.e3.
  7. Yin C, Li Z, Xiang Y, et al. Effect of Intermittent Fasting on Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis. Front Nutri. 2021;8:709683
  8. Bowen J, Brindal E, James-Martin G, et al. Randomized Trial of a High Protein, Partial Meal Replacement Program with or without Alternate Day Fasting: Similar Effects on Weight Loss, Retention Status, Nutritional, Metabolic, and Behavioral Outcomes. Nutrients. 2018;10(9):1145.
  9. Zhou ZL, Jia XB, Sun MF, et al. Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson’s Disease Mice via Gut Microbiota and Metabolites. Neurotherapeutics. 2019;16(3):741-760.
  10. Mindikoglu AL, Abdulsada MM, Jain A, et al. Intermittent Fasting From Dawn to Sunset for Four Consecutive Weeks Induces Anticancer Serum Proteome Response and Improves Metabolic Syndrome. Sci Rep. 2020;10(1):18341.
  11. Fernández-Cardona A, González-Devia D, Mendivil CO. Intermittent Fasting as a Trigger of Ketoacidosis in a Patient With Stable, Long-term Type 1 Diabetes. J Endocr Soc. 2020;4(10):bvaa126.
  12. Rajpal A, Ismail‐Beigi F. Intermittent Fasting and ‘Metabolic Switch’: Effects on Metabolic Syndrome, Prediabetes and Type 2 Diabetes. Diabetes Obes Metab. 2020;22(9):1496-1510.
  13. Aoun A, Ghanem C, Hamod N, et al. The Safety and Efficacy of Intermittent Fasting for Weight Loss. Nutrition Today. 2020;55(6):270-277.

Disclosure statements are available on the authors' profiles:

Robert Bonakdar MD, FAAFP, FACN

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