Michael C. Honigberg MD, MPP, FACC
Assistant Professor of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Associate Member, Broad Institute of MIT and Harvard, Cambridge, MassachusettsMichael Honigberg, MD, MPP, FACC, is a physician-scientist in the Cardiology Division at Massachusetts General Hospital, Assistant Professor of Medicine at Harvard Medical School, and Associate Member of the Broad Institute of MIT and Harvard. He received his AB in public policy summa cum laude and Phi Beta Kappa from Princeton University and his MD from Harvard Medical School. He completed internship and residency in internal medicine at Brigham and Women’s Hospital in 2017 and completed clinical and research fellowship in cardiovascular medicine at Massachusetts General Hospital in 2020.
Dr. Honigberg’s research combines classical epidemiology with human genomics, multi-omics approaches, and imaging to (1) elucidate sex-specific risk factors for cardiovascular disease in women and their underlying mechanisms, (2) improve cardiovascular risk prediction and allocation of existing and novel preventive therapies, and (3) define precision strategies for cardiovascular risk reduction in at-risk populations. His recent work has focused on defining the cardiovascular consequences of preeclampsia and premature age of menopause, including defining germline and somatic genomic factors that contribute to heightened cardiovascular risk in affected women, and on the cardiovascular consequences of clonal hematopoiesis of indeterminate potential (CHIP), the clonal expansion of blood stem cells harboring pre-leukemic driver mutations. He recently led an expanded genome-wide association study (GWAS) of preeclampsia and the first distinct GWAS of gestational hypertension, yielding new insights into shared genetic risks with cardiovascular disease. His research program is supported by the U.S. National Heart, Lung, and Blood Institute and the American Heart Association.
Complementary to his research efforts, Dr. Honigberg provides care for patients through the MGH Cardiovascular Disease Prevention Center, Women’s Heart Health Program, and inpatient teaching services and directs the core Prevention, Genetics, and Women’s Heart Health rotation for MGH cardiology fellows. He is the recipient of the Roman DeSanctis Clinical Scholar Award, the Jeremiah Stamler Award from the Northwestern Cardiovascular Young Investigators’ Forum, and the 2023 Douglas P. Zipes Distinguished Young Scientist Award from the American College of Cardiology.