Alison P. Klein MHS, PhD
Division of Gastroenterology, Department of Medicine, Johns Hopkins School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, Johns Hopkins School of Medicine; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MarylandDr. Klein is a Professor of Oncology, Pathology and Medicine at Johns Hopkins School of Medicine with at Joint appointment in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. She has studied the genetic epidemiology of pancreatic cancer for over 20 years. Her research focuses on the discovery of pancreatic cancer susceptibility genes sequencing and association approaches as well as quantification of pancreatic cancer risk due to familial and genetic factors. She has identified rare variants in PALB2 and ATM are associated with pancreatic cancer as well as lead large-scale genome wide association studies of pancreatic cancer risk. Dr. Klein is the Director of the National Familial Pancreas Tumor Registry, the largest single-site registry of familial pancreatic cancer in the world. Currently, over 7,700 families have enrolled in this registry including over 2,000 with familial pancreatic cancer (i.e., defined as a kindred with at least a pair of first-degree relatives with pancreatic cancer).
She co-leads the Sidney Kimmel Comprehensive Cancer Center Cancer Prevention and Control Program. She also directs the Johns Hopkins SPORE in Gastrointestinal Cancer.